Distributed quantum architectures with arbitrary network topology can now be optimized for large-scale fault-tolerant quantum computation through Clifford circuit synthesis. This approach enables the combination of multiple small qubit sets, leveraging quantum error correction with block codes or shared entanglement in distributed quantum processors. By focusing on non-local operations, researchers can better manage time and error budgets in quantum computations. The development of such architectures is crucial for overcoming scalability limitations in current quantum computing systems. Specifically, this method allows for more efficient distribution of quantum information across the network, reducing the impact of errors and improving overall computation reliability1. This breakthrough has significant implications for the future of quantum computing, as it paves the way for more robust and efficient large-scale quantum computations, which in turn will redefine the boundaries of cryptography and computational power, making it essential for practitioners to stay informed about these advancements.