ClinFusion, a novel multimodal large language model system, has been designed to tackle the complexities of medical understanding by integrating knowledge from diverse 2D and 3D medical images. This vision-centric approach enables the model to align with radiologists' clinical practices, providing a more accurate and fine-grained assessment of medical conditions. By leveraging advancements in large language models, ClinFusion has the potential to revolutionize clinical practice by enhancing diagnostic capabilities and streamlining medical decision-making processes. The system's ability to absorb and process heterogeneous medical images is a significant step forward in the development of AI-powered medical diagnostic tools1. As the medical community continues to adopt AI-driven solutions, ClinFusion's vision-centric approach may become a crucial component in the development of more effective and efficient clinical practice protocols. The successful deployment of such a system could significantly impact the field of medical diagnostics, enabling practitioners to make more informed decisions and improve patient outcomes.