Osaka University's Center for Quantum Information and Quantum Biology and Fixstars Corporation have successfully simulated a quantum chemistry simulation beyond the 40-qubit threshold, setting a new benchmark in classical quantum simulation1. This achievement demonstrates the ability to handle larger qubit counts and more complex Hamiltonian terms, resulting in deeper circuits and longer simulation times. The simulation of IQPE quantum circuits marks a significant milestone in the development of quantum computing, as it pushes the boundaries of what is currently possible with classical systems. The breakthrough has significant implications for the field of quantum chemistry, where accurate simulations of complex molecular interactions are crucial. As quantum computing continues to advance, it is likely to challenge existing assumptions about computation and cryptography, making it essential for practitioners to stay informed about the latest developments. This milestone matters to practitioners because it underscores the rapidly advancing capabilities of quantum simulation, which will eventually impact the security and efficiency of various computational tasks.